People should lend him a helpful hand；he's really down and out
人们应该助他一臂之力，他已经穷困潦倒了
The fates mess around with the people who have the most to lose.
灾难总是同穷困潦倒的人形影不离。
Vagrant, usually destitute people.
无业游民通常指穷困潦倒的人
Lacking funds, resources, or prospects; destitute.
穷困潦倒的缺乏基金、资源或前途渺茫的；缺乏的
A homeless person, especially an impoverished vagrant.
流浪汉无家可归的人，尤指穷困潦倒的流浪者
Many countrys in the world, people do not shake off a dog's life all the same.
在世界上许多国家，人们仍然没有摆脱穷困潦倒的生活。
Now, they really were poor.
它们现在可真的是穷困潦倒了。
He was on his uppers when I came across him.
我是在他穷困潦倒时碰见他的。
During one winter in Chicago, he was cold and poor,
芝加哥的某年冬天，他穷困潦倒，
If I feel poverty I will think of wealth to come.
穷困潦倒时，我想象未来的富有。
Your reckless spending will beggar your father.
你无度的挥霍将使你父亲穷困潦倒。
from being a poor poverty-stricken boy in the morning,
汤姆早上还是个贫困潦倒的穷小子，
He looked completely down and out.
他看上去已穷困潦倒.
He has been brought low by misfortune.
他因遭厄运而穷困潦倒。
down and out
穷困潦倒,孤苦无助
The California earthquake left many people down and out.
加利福尼亚洲的地震使许多人（变得）穷困潦倒。
The writer's family descended in the end to extreme poverty.
那位作家一家人后来穷困潦倒了。
Sarah was down and out after losing her job and her apartment.
萨拉丢掉工作和房子后变得穷困潦倒。
Mr Foley was down and out after he lost many friends.
佛利先生失去许多朋友之后，穷困潦倒。