Objective: To explore the TCM symdrome pattern at different stages of diabetes mellitus and the relevance with differentially expressed genes using a monozygotic twin as model.
方法:首先,卵型鉴定处于患糖尿病不同发展阶段的双生子对;其次,采用158项的六纲调查量表和68项的肾虚量表评分不同时间段的肾虚证候;最后应用基因芯片技术,筛选这对单卵双生子之间的差异表达基因谱,并进行数据分析。
Objective To analyze environmental factors of the discordance of concomitant strabismus phenotypes in monozygotic twins.
①目的通过分析单卵双胎儿表型不一致性共同性斜视发病因素,探讨其发病机制。
Methods About 142 pairs of monozygotic (MZ) twins and 86 pairs of dizygotic (DZ) twins aged 5-19 were studied.
方法 选取 5～ 1 9岁双生子 2 2 8对 ,其中MZ(单卵双生子 ) 1 4 2对 ,DZ(二卵双生子 ) 86对 ,在DNA卵性鉴定基础上 ,以成对法计算同病一致率、调整BMI前后组内相关系数及遗传度。
Objective To study the incidence and potential mechanism of monozygotic twins(MZT) pregnancies in IVF-ET cycles.
目的探讨体外受精-胚胎移植技术(IVF-ET)中单卵双胎妊娠的发生率及可能的机制。
Study on Chromosome Preparation of Single Blastomere from Mouse 4、8-Cell Stage Embryos;
小鼠4、8-细胞期胚胎单卵裂球染色体标本制备的研究
Conclusion:Single blastomere PCR is stable and reliable,and it can be used for preimplantation genetic diagnosis.
目的建立单卵裂球PCR技术,为开展单基因病的着床前遗传学诊断奠定基础。