The regulating mechanism of the balance between bone resorption and bone formation by the mechanical stimulation was investigated through gene expression of osteoprotegerin(OPG) and osteoclast differentiation factor(ODF).
本研究以Wistar 大鼠颅骨成骨细胞为研究对象,通过流动腔装置施以流体剪应力,从细胞的增殖、分化、矿化和形变研究成骨细胞对流体剪应力的响应,从骨保护因子(OPG),破骨细胞分化因子(ODF)的基因表达研究力学刺激对骨吸收和骨形成平衡的调控,最后尝试成骨细胞对破骨细胞形成的诱导作用,进一步考察了力学刺激影响骨代谢平衡的可能途径。
Effect of estrogen on osteoprotegerin, osteoclast differentiation factor and macrophage colony stimulating factor mRNA expressions in ovariectomized rat bone tissue;
雌激素对去卵巢大鼠骨组织中骨保护素、破骨细胞分化因子和巨噬细胞集落刺激因子mRNA表达的影响
Expression of osteoclast differentiation factor and its receptor and decoy receptor in giant cell tumor of bone;
破骨细胞分化因子及其受体和反意受体在骨巨细胞瘤中的表达及意义
Immunocytohistochemical Location of Osteoclast Differentiation Factor in Experimental Periapical Lesions;
根尖周病变中破骨细胞分化因子的免疫组化定位
Study on the Mechanism of RANKL in Bone Absorption of Periapical Lesion;
破骨细胞分化因子在根尖周骨吸收中的作用机制研究
Effects of Calcitonin on RANKL;
降钙素对小鼠牙齿萌出过程中破骨细胞分化因子RANKL表达的影响
Methods:The expression of osteoprotegerin(OPG),receptor activator of nuclear factor(NF)-kappaB ligand(RANKL),interleukin-6(IL-6) and estrogen receptor-alpha(ER-α) was detected by using RT-PCR and Western blot in hOB.
方法:采用细胞培养结合RT-PCR、Westernblot技术观察金雀异黄素对护骨素(OPG)、破骨细胞分化因子(RANKL)、白介素-6(IL-6)等基因mRNA及蛋白质表达。
Expressions of ODF and OCIF in human periodontal ligament cells and human gingival fibroblasts
破骨细胞分化因子和破骨细胞生长抑制因子在牙周组织细胞中的表达
Expression of RANK-RANKl-OPG system in middle ear cholesteatoma
破骨细胞分化因子及其相关因子在中耳胆脂瘤组织的表达
Construction of Human Osteoclast Differentiation Factor Vector and Study of It Preliminary Expression;
人破骨细胞分化因子（ODF）重组表达载体的构建及其表达的初步研究
Effects of Calcitonin on RANKL;
降钙素对小鼠牙齿萌出过程中破骨细胞分化因子RANKL表达的影响
Study of Expression of ODF and OCIF during Orthodontic Periodontium Remodeling;
正畸牙周组织改建中破骨细胞分化因子和发生抑制因子表达的研究
Expression of NFATc1 in titanium particle-induced osteoclasts formation
钛颗粒诱导破骨细胞分化过程中活化T细胞核因子c1的表达
The transduction pathway of osteoblasts and osteoclasts and related factors
成骨细胞和破骨细胞的传导通路和相关因子
Molecular Mechanisms of Osteoclastgenesis and Local Modulation of Osteoclast Differentiation and Activity in Osteolytic Diseases;
破骨细胞形成的分子机制及溶骨性病变中破骨细胞的局部调控
Osteoclast Differentiation Regulated by Receptor Activator of Nuclear Factor κB Probably Through A Novel Signaling Pathway
核转录因子κB受体激活剂可能通过新的信号途径调节破骨细胞分化
Expression, Purification and Function of Osteoprotrgerin;
破骨细胞形成抑制因子（OPG）的表达纯化及功能研究
EXPERIMENTAL STUDY ON CHONDROGENIC DIFFERENTIATION OF RABBIT ADIPOSE-DERIVED STEM CELLS TREATED WITH GROWTH DIFFERENTIATION FACTOR 5
生长分化因子5诱导兔脂肪干细胞成软骨细胞分化的实验研究
Characteristics of osteoclast in process of differentiation and formation;
破骨细胞分化、形成过程中表现型特点
Conclusion The sensitized T lymphocytes could promote osteoclastic differentiation and the ability of bone resorption.
结论:致敏淋巴细胞能够促进骨髓破骨细胞的分化和骨吸收能力。
Influnce of OPG and RANKL on duck′s osteoclasts formation and activation in vitro
骨保护素和核因子κB受体活化因子配基对体外培养鸭破骨细胞的影响
Differentiation of Rat ADSCs into Chondrocytes Transfected by SOX-9 and TGF-β1 Gene Alone and Together
SOX-9和转化生长因子-β1共同诱导大鼠脂肪干细胞向软骨细胞分化
The Differentiation and Formation of Mouse Osteoclast-like Cell Inhibited by NF-κB Gene Silencing;
NF-κB基因沉默对小鼠破骨样细胞分化形成的影响
Growth differentiation factor 5 induces the chondrogenesis of precartilaginous stem cells in rats
生长分化因子5诱导大鼠软骨前体细胞向成软骨方向分化
Effect of Glucose on the Differentiation and Activation of Osteoclast Derived from Rat Bone Marrow Cells;
葡萄糖对大鼠骨髓破骨细胞分化及活性的影响