Autosomal dominant congenital nuclear cataract caused by a deletion mutation in the βA1-crystallin gene;
晶体蛋白βA1基因缺失突变导致常染色体显性遗传核性先天性白内障
Objective To search parkin gene deletion mutations at exons 1 to 6 in Chinese patients with praecox Parkinson s disease (PPD) and analyze them together with the clinical features of PPD.
方法 用 PPD患者外周血液提取 DNA,通过 PCR扩增、琼脂糖凝胶电泳鉴定 parkin基因外显子缺失突变 ,并结合临床资料分析。
Objective To characterize the deletions of mitochondrial DNA (mtDNA) in Chinese patients with Kearns-Sayre syndrome (KSS) and chronic progressive external ophthalmolegia (CPEO) and identify deletion mutations of mtDNA be the etiology of these diseases.
在2例Kearns－Sayre综合征（KSS）和2例慢性进行性眼外肌麻痹（CPEO）患者的骨骼肌线粒体DNA（mtDNA）中发现存在单一的大片段缺失突变。
Aim: To study the application of the mutation-sensitive molecular switch in the two deletion hotspots of EGFR gene associated with lung cancer.
目的:研究高保真DNA聚合酶介导的基因突变敏感性分子开关在肺癌EGFR基因缺失突变检测中的应用。
Construction and characterization of EHEC O157∶H7 ler gene deletion mutant;
肠出血性大肠杆菌O157 ler基因缺失突变株的构建及其特性
In order to determine the effect of stx gene of EHEC O157∶H7, stx deletion mutant was constructed.
针对肠出血性大肠杆菌 (EHEC) O1 5 7∶H7的 stx基因 ,通过 PCR扩增出缺失了 1 83bp的 stx基因片段 ,将其克隆到自杀性载体 p CVD4 4 2中 ,然后通过接合性转导将重组自杀性质粒 p CVD4 4 2∷Δstx从大肠杆菌 SM1 0转到 O1 5 7∶ H7中 ,利用抗性标记和 PCR方法筛选出 O1 5 7∶ H7stx基因缺失突变菌株。
To investigate whether the binding of Grp75 and p53 would influence the viability of cells, we constructed the eukaryotic expression vector of Grp75 deletion mutant.
为研究Grp75和p53的结合与否是如何影响细胞活力,现构建Grp75缺失突变基因的真核表达载体。
Objectives: To study the association between the etiology and the deletive mutations of exons 1 to 7 on Parkin gene patients with praecox Parkinson s disease (PPD) in GuangXi and analyze the clinical features of PPD.
目的：研究Parkin基因1～7号外显子缺失突变与广西地区早发性帕金森病(PPD)的关系；分析PPD相关的临床特点。
excision repair deficient mutant
剪切修复缺失突变型
Construction of Streptococcus mutans comE Mutant Strain Using In-frame Deletion System
框内缺失突变法构建变形链球菌comE基因突变株
Studies on Detection of Deletion Mutation of Human Mtiochondrial DNA;
人线粒体DNA缺失突变检测的研究
Clinical Study on Parkin Gene Deletion Mutations in Chinese Patients with Parkinson s Disease;
帕金森病Parkin基因缺失突变的临床研究
Study on mitochondrial DNA deletion in aging mice
衰老小鼠线粒体DNA缺失突变的研究
Construction of Goatpox Virus Gene Deleted Transfer Vector and Generation of Gene Deleted Mutant;
山羊痘病毒基因缺失转移载体及基因缺失突变毒株的构建
Molecular Analysis of Activation Tagging Library and Characterization of a Mutant Lacking the Apical Dominance in Arabidopsis Thaliana;
拟南芥激活突变体库及顶端优势缺失突变体的分子分析
Immune Responses to Plasmid DNA Encoding the Hepatitis C Virus Core Deletion Mutant in Mice;
缺失突变HCV核蛋白DNA免疫效果的初步评价
Genetic Analysis and Mapping of Soybean Lipoxygenase-null Mutation Gene;
大豆脂氧酶缺失突变基因的遗传分析与定位
Generation of a gE/TK-Gene-Deleted Mutant Derived from Pseudorabie Virus Bartha-K61 Strain;
伪狂犬病病毒gE/TK基因缺失突变株的构建
Recombination and Expression of SM22α and Its Deleted Mutant and Study of Their Functions;
SM22α及其缺失突变体的重组表达和功能研究
Construction of Deletion Mutants of CUE Domain Containing 2(CUEDC2) and Preliminary Research of Its Function;
CUEDC2各种缺失突变体的构建及其功能初探
Characterization of Bacillus thuringiensis spoⅢD gene Mutantation
苏云金芽胞杆菌spoⅢD基因缺失突变株的特点
Construction of z3672 deletion mutant of EHEC O157∶H7 EDL933w
大肠杆菌O157∶H7 EDL933wz3672基因缺失突变体的构建
Catalytic properties of 338Val-deleted mutant of 4-coumarate:coenzyme A ligase from Populus tomentosa.
毛白杨4-香豆酸:辅酶A连接酶338Val缺失突变分析
Construction of Rhodopseudomonas palustris hupL gene deficient mutant with higher efficient of H_2 production
沼泽红假单胞菌高效产氢hupL缺失突变株的构建
Construction of Saccharomyces cerevisiae Mutant Deficient in adh2 and ald6 Genes
酿酒酵母adh2和ald6双基因缺失突变株的构建
5′ UTR deletion analysis of porcine reproductive and respiratory syndrome virus
PRRSV感染性克隆5′非翻译区序列缺失突变分析