Chromosome painting was performed using whole chromosome probes 9 and 12.
方法患者骨髓细胞短期培养后按常规方法制备染色体,采用R显带技术进行染色体核型分析;以9 号和12 号整条染色体涂染探针对其进行染色体涂染检测。
Objective To report five cases of acute myeloid leukemia(AML) with t(16;21)(p11;q22) translocation and the result of chromosome painting analysis on one of them.
目的 报告 5例伴有t( 16;2 1) ( p11;q2 2 )的急性白血病和其中 1例的染色体涂染分析。
Chromosome painting is a technique for labelling metaphase chromosomes and interphase nuclei by fluorescence in situ hybridization(FISH),using whole or partial chromosome painting probes.
染色体涂染 ( Chrom som e painting) 是一项在分子细胞遗传学水平上检测染色体重组和畸变的新技术, 包括染色体涂染 D N A 探针制备和荧光标记原位杂交两部分。