On isomerization of retinal portion in rhodopsin;
紫红质色基-视黄醛骨架异构化机理探讨
The proton transfers among Asp85, Asp212, water and retinal were analyzed through the change of separation distance.
用CHARMM程序以细菌紫红质1R84晶体为模型,模拟了在等温定容条件下细菌紫红质在1ps过程中的变化,分析了与质子传递相关的ASP85,ASP212和水分子与视黄醛间氢键的结构变化情况。
A series of structural changes triggered when absorption of light energy caused isomerization of bacteriorhodopsin s bound retinal,and protons were transported from the inside of the cell to the out side medium and thereby converted light energy into chemical energy which enables the halobacterium to survive.
细菌视紫红质(Bacteriorhodopsin,或bR)是盐生嗜盐菌(Halobacterium salinarium)等细菌的跨膜蛋白质,其色基视黄醛的光致异构化作用触发细菌视紫红质的一系列结构变化,把质子从细胞质泵到细胞外空间。