To identify the neurochemical mechanisms of the audiogenic kindling in the forebrain structures, the expression of c fos gene, a marker of neuronal activity, and the level of brain derived neurotrophic factor (BDNF) in the neocortex were studied after single and kindled audiogenic seizure with immunocytochemistry method.
为探讨前脑结构参与听源性惊厥点燃过程的神经化学机制 ,本研究以 c-fos基因表达作为神经元功能活动的标志 ,采用免疫细胞化学方法 ,对新皮质内参与听源性惊厥点燃过程的神经元的分布状况进行了观察 ,并对相关区域内脑源性神经营养因子表达水平的变化进行了分析。
An investigation on the relations between synchronized oscillations and epileptogenesis induced by repeatedly delivering tetanus into the hippocampus and medial temporal neocortex in rats;
强直电刺激大鼠海马、中部颞叶新皮质诱发癫癎模型中电振荡与癫癎发生的关系研究(英文)