AMPA

The majority of AMPA receptor is a GluR 2 - containing heterotetramer in hippocampus.

在海马中大部分AMPA受体是以含 GluR2 的异四聚体的形式存在.

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When AMPA receptor is activated, lots of intracellular Ca ~ ( 2 + ) result in neurons injury.

在AMPA受体激活时, 大量 Ca2 +内流导致神经损伤.

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GluR 2 - lacking AMPA receptors appeared high permeability to Ca 2 +.

缺乏GluR2的AMPA受体通道对Ca2+有很高的通透性.

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Objective To explore the epileptogenesis effect of the AMPA receptors.

目的　为了研究AMPA受体在癫痫发生中的作用.

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These attach themselves to nerve - cell proteins called AMPA receptors.

这些依附于神经元细胞自己的叫做AMPA接收器.

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AMPA receptor has the important role in epilepsy about its pathogenesis study and therapy.

AMPA受体 对于癫痫发病机制的研究和治疗均有重要作用.

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At these synapses , most of baseline synaptic transmission is mediated by glutamate AMPA receptors.

在正常条件下, 大多数的突触反应是由谷氨酸的AMPA受体传递的.

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AMPA receptors mediate the fast excitatory synaptic transmission in the central nervous system.

AMPA受体介导了中枢神经系统绝大部分快速型的兴奋性突触传递.

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Objective To investigate the role of changes in AMPA receptor GluR 2 subunit expression in epileptogenesis.

目的研究在癫痫发病过程中,谷氨酸对AMPA受体GluR2亚单位表达变化的影响.

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The suitable concentration of AMPA is 2.3μ M, which leaded to the Ratio of 0.8±0.14.

AMPA作用的最适浓度为2.3μM, 反映细胞内[Ca2+]高低的指标—Ratio值约为0.80±0.14.

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The nature AMPA receptor is normally Ca ~ ( 2 + ) impermeable due to the expression of GluR 2 subunit.

由于GluR2亚单位的表达天然AMPA受体通道对 Ca2 +不通透.

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