In oral formulation, ximelagatran converts to the active form melagatran in the body,which acts by binding reversibly to alpha-thrombin and inhibiting both free and clot bound thrombin.
服给药后迅速吸收,与食物及其他药物相互作用较小,迅速转化为有效的活性中间产物美加拉群(melagatran),通过抑制人α-凝血酶的活性产生抗凝作用。
Anticoagulant effect of direct thrombin inhibitor ximelagatran on atrial fibrillation;
直接凝血酶抑制药希美加群在心房颤动抗凝治疗中的应用
This article introduces the pharmacodynamic and pharmacokinetic properties of ximelagatran and gives a brief description of some relevant clinical trials.
希美加群是一种新型的口服抗凝剂。
There were four more stops on the way up the western coast of Chile,
小船在沿智利和秘鲁西海岸上行过程中又停留了四次，然后在加拉帕戈斯群岛停下来。
Diesel Spill in the Sea Threatens Ecosystem in Galapagos Islands
柴油翻漏海中威胁加拉巴戈斯群岛生态
very large tortoises of the Galapagos and Seychelles islands.
产于加拉帕哥斯和塞舌尔群岛的非常大龟。
But some live near warm waters in the Galapagos Islands, near the coast of Ecuador.
但是有些生活在厄瓜多尔海岸附近加拉帕哥斯群岛的暖水域。
shore-dwelling seaweed-eating lizard of the Galapagos Islands.
产于加拉帕哥斯群岛的栖息于海滨并以海藻为食的蜥蜴。
A visit to the Galapagos Islands might also satisfy an ecologically-minded person like yourself.
加拉帕哥斯群岛的生态游也一定能让你大呼过瘾。
The spilled diesel is not bad enough to threaten the wildlife native to the Galapagos Islands.
溢漏的柴油不至于会对加拉巴戈斯群岛独特的野生动植物造成威胁。
It was Darwin's visit on the Beagle to the Galapagos Isles that gave him the key to his new theory.
达尔文乘“小猎犬号”去加拉戈斯群岛的活动使他获得了新创建理论的钥匙。
Galapagos Declaration: Andean Agreement on Peace,Security and Cooperation
加拉帕戈斯宣言：关于和平、安全与合作的安第斯协议
At the Galapagos Rift, volcanic activity beneath two geologic plates renews the earth's crust.
在加拉帕戈斯裂谷，两地质板块下面的火山活动使地壳更新。
a republic in the West Indies; located on the east of the island of Hispaniola.
西印度群岛上的一个共和国；位于伊斯帕尼奥拉岛东部。
a republic in the West Indies on the island of Hispaniola; the poorest nation in the Western Hemisphere.
位于西印度群岛的一个共和国，在伊斯帕尼尔奥拉群岛上；西半球最穷的国家。
a member of the people inhabiting the Aleutian Islands and W Alaska.
生活在阿留申群岛和阿拉斯加州的民族的人。
2 Tropical Storm Noel is dropping heavy rain on portions of Cuba, the island of Hispaniola and the Bahamas.
热带风暴诺尔给古巴部分地区、伊斯帕尼奥拉岛和巴哈马群岛带来了强降雨。
During the 17th and mid19th the Russian territory expanded to The Kurile Islands and Alaska.
17-19世纪中期,沙俄势力扩张至千岛群岛和阿拉斯加。
Unda said the Ecuadorian government must "improve the port facilities at the Galapagos Islands to prevent such oil spill accidents from happening again."
恩达说，厄瓜多政府必须「改进加拉巴戈斯岛屿的港口设施，以免这类漏油意外的重演」。
We are descending into the Galapagos Rift Valley.
我们现在朝向加拉巴戈斯裂谷沉下。
re-development of Port-City in Las Palmas,Gran Canaria 2001-2009
金丝雀岛拉斯帕尔马斯港区再开发方案