Objective: To develop a method so as to determine the related substances in the temozolomide hexyl ester.
目的:建立替莫唑胺酯中有关物质的测定方法。
Room temperature ionic liquids(IL)of(bmim)PF_6 was synthesized from N-methylimidole by two steps:quaternization and metathesis,and the conversion ratio was determined by Mohr method.
用两步法合成了离子液体(bmim)PF_6,莫尔法测定了N-甲基咪唑的转化率,结果发现在第一步季铵化反应过程中,不添加任何有机溶剂,在60℃下反应1h,可获得高达96。
The conversion ratio was determined by Mohr method.
用两步法合成离子液体(emim)BF4,以莫尔法测定N-甲基咪唑的转化率。
RP-HPLC Diode Array Detector for Determination of the Related Substances in the Temozolomide Hexyl Ester
反相离子对色谱二极管阵列检测器测定替莫唑胺酯原料的有关物质
Chemotherapy as initial treatment in gliom-atosis cerebri: Results with temozolomide
脑神经胶质瘤病首选化疗:替莫唑胺的疗效
Clinical Observation in Chemotherapy with Temozlimide in Postoperative Primary Cerebral Glioma;
原发性脑胶质瘤术后替莫唑胺化疗的临床观察
Prelinimary Studies on Temozolomide Delayed Release Microspheres Against Glioma
替莫唑胺缓释微球治疗胶质瘤的实验研究
Clinical study of temozolomide for refractory malignant glioma
替莫唑胺治疗难治性恶性脑胶质瘤临床观察
Proliferating changes of human neuroblastoma cell line U251 cells treated with temozolomide
替莫唑胺对人胶质瘤细胞系U251细胞的增殖影响
A Clinical Study of Temozolomide vs. Semustine in Patients with Malignant Gliomas;
应用替莫唑胺对照司莫司丁治疗恶性脑胶质瘤的临床研究
Synthesis and Characterization of Anticancer Temozolomide Coupled with Nitric Oxide Donors;
抗肿瘤药替莫唑胺一氧化氮供体型衍生物的合成与表征
The Expression and Significance of MGMT in the Treatment of Malignant Glioma by Temozolomide;
MGMT在替莫唑胺（TMZ）治疗恶性脑胶质瘤中的表达及意义
The Effect of the Temozolomide in Exclusively Chemotherapy/in Radio-Chemotherapy Combined Treatmeng for the Intracal Glioblastoma after Operation;
颅内恶性胶质瘤术后替莫唑胺单纯化疗/联合放疗的疗效观察
Experiment Study of Temozolomide/PLGA Microspheres Chemotherapy in Treatment of C6 Rat Glioma;
替莫唑胺缓释微球治疗大鼠C6胶质瘤的实验研究
High Potency of Lidamycin on Glioma Suppression and Its Synergism with Temozolomide: Involvement of Enhanced Antiangiogenesis and Apoptosis Induction
力达霉素对神经胶质瘤抑制作用及联合替莫唑胺的协同作用研究
Temozolomide United rituximab in the treatment of recurrent Central nervous system lymphoma(a case report)
替莫唑胺联合美罗华治疗复发中枢神经系统淋巴瘤(附1例报告)
The Clinical Analysis to Temozolomide Plus Concomitant Radiotherapy in the Treatment of Lung Cancer with Brain Metastases
替莫唑胺同步放疗治疗肺癌脑转移临床分析(附35例报告)
Therapeutic effect of local implantation with temozolomide/PLGA microsphere in treatment of rat C6 glioma in vivo
替莫唑胺缓释微球局部植入治疗大鼠脑胶质瘤的疗效
A Clinical Study of Three-dimensional Conformal Radiotherapy with Temozolomide in Treatment of Postoperative Malignant Glinoma
三维适形放疗联合替莫唑胺治疗恶性脑胶质瘤的临床研究
Correlation of O~6-Methylguanine-DNA Methyltransferase with Prognosis of Malignant Glioblastoma Patients Treated with Temozolomide
MGMT在恶性胶质瘤中的表达对替莫唑胺化疗预后的影响
Effects of temozolomide on patients with malignant gliomas
替莫唑胺在恶性胶质瘤综合治疗中的临床疗效观察