Improvement in synthesis of the intermediate of pitavastatin;
匹伐他汀中间体的合成工艺改进
Determination of pitavastatin in human plasma by liquid chromatographytandem mass spectrometry;
液相色谱-串联质谱法测定人血浆中匹伐他汀
Effect of different dosages of pitavastatin on blood flow recovery in ischemic limbs of mice;
不同剂量匹伐他汀对小鼠缺血肢血流恢复的影响
The synthesis routes and research advance of plasma lipid regulators: pitavastatin calcium were reviewed with 21 references.
综述了降血脂药物匹伐他汀钙的合成方法和最新研究进展。
This method is improved for preparing the intermediate of pitavastatin calcium by the reaction of L-(-)-malic acid through methyl esterification,selective reduction,trityl protection,Claisen condensation,stereoselective reduction,ketalization,deprotection of trityl and Swern oxidation.
以L-(-)苹果酸为起始原料,经甲酯化、硼烷选择性还原、三苯甲基保护、克莱森酯缩合、立体选择性还原、缩酮保护、脱三苯甲基保护、斯文氧化制得匹伐他汀钙重要中间体(3R,5S)-3,5-二羟基-6-氧代-3,5-O-亚异丙基己酸叔丁酯,收率为21。
A RP-HPLC method was established for the determination of the related substances in pitavastatin calcium.
建立了RP-HPLC法测定匹伐他汀钙有关物质。
Pitavastatin enhances angiogenesis and perfusion in a murine model of limb ischemia;
匹他伐他汀促进小鼠血管新生作用及其机制的研究
Effect and Mechanism of Pitavastatin in Therapeutic Angiogenesis Study;
匹他伐他汀对实验性血管生的作用及其作用机制的研究
Study on Bioequivalence of pitavastatin capsules in Chinese Healthy Volunteers
匹伐他汀钙胶囊人体生物等效性研究
Therapeutic effects and safety of domestic pitavastatin and simvastatin on hyperlipidemia
匹伐他汀与辛伐他汀治疗高脂血症疗效和安全性比较
HPLC determination of pitavastatin in human plasma
高效液相色谱法测定人血浆中匹伐他汀浓度
Effect of the Oil of Grape Seeds on the Pharmacokinetics of Pitavastatin in Healthy Volunteers
刺葡萄籽油对匹伐他汀健康人体药动学的影响
The Distribution of SLCO1B1 in Chinese Hyperlipemia Patient and the Impact of Its PolymorpHism on Efficacy of Pitavastatin;
中国高脂血症病人SLCO1B1分布及其多态性对匹伐他汀疗效的影响
An Experimental Study on the Lipid-modulating Effects and Safety of Domestic Pitavastatin Calcium;
国产匹伐他汀钙片调脂疗效及安全性的试验研究
Research on the Discrepancy of Lipid-lowering Effect in Primary Hypercholesterolemia Patients Treated by Pitavastatin;
匹伐他汀对高胆固醇血症患者降脂疗效差异的相关研究
A simple and sensitive LC-MS/MS method for determining the concentration of pitavastatin in human plasma
简单灵敏的LC-MS/MS方法检测人血浆匹伐他汀浓度
Effects of high fat diet on pharmacokinetics of pitavastatin and its lactone in Chinese healthy volunteers
高脂餐对匹伐他汀及其内酯代谢物的人体药动学影响
The Control Study of the Effects of Pitavastatin on Rats with Acute Myocardial Infarction;
匹伐他汀对急性心肌梗死大鼠血清中细胞因子表达干预作用的对照研究
THE OUTCOME OF LARGE-DOSE ASPIRIN COMBINED WITH FLUVASTATIN SODIUM FOR TRANSIENT ISCHEMIC ATTACK
大剂量阿司匹林并氟伐他汀钠治疗TIA效果
Effect and Mechanism of Pitavastatin in Therapeutic Angiogenesis Study;
匹他伐他汀对实验性血管生的作用及其作用机制的研究
Aspirin Increase the Medicative Effect of Simvastatin on Atherosclerosis;
阿司匹林加强辛伐他汀的抗动脉粥样硬化作用及机制
Inhibitory Effects of Aspirin, Simvastatin, and Their Combination on the Progression of Atherosclerosis in Rabbits;
阿司匹林、辛伐他汀及合用对兔动脉粥样硬化病变进展的抑制作用
Clinical Observation in Patients with Refractory Hypertension Treated Assistantly in Aspirin Simvastatin Ginaton
阿司匹林辛伐他汀金纳多联合佐治难治性高血压临床疗效观察
Effects of intervention with Simvastatin and Aspirin on carotid artery atherosclerosis
辛伐他汀及阿司匹林干预对颈动脉粥样硬化的影响
The Effects of Atorvastatin and Aspirin on MPO and SOD in Rats Following Cerebral Ischemic Reperfusion
阿托伐他汀与阿司匹林对大鼠脑缺血再灌注后MPO、SOD影响的研究
Pravastatin vs. Simvastatin in Lipid-regulating Efficacy and Safety
普伐他汀与辛伐他汀的调脂疗效与安全性比较