Objective: To synthesize roxatidine acetate and its salt; to design and synthesize phenoxypropylamines and observe their effect on the inhibition of gastric juice acid.
目的:合成H_2受体阻滞剂罗沙替丁乙酸酯盐酸盐;设计合成具有抑酸活性的苯氧丙胺类化合物,并考察其体外抑酸活性。
The pharmacological peculiarity of the fourth histamine H_2-Receptor antagonists(Roxatidine acetate) is described in much detail.
本文系统地介绍了消化性溃疡的发病机理以及H_2-受体拮抗剂在消化性溃疡中的治疗作用，详细地阐述了第四代H_2-受体拮抗剂罗沙替丁乙酸酯(Roxatidine Acetate)的药理作用和特点，对罗沙替丁乙酸酯的合成工艺进行了考察，确定了较好的反应条件，得到了罗沙替丁乙酸酯的盐酸盐，四步反应总收率为29％，产品结构经波谱测试，结果与文献值一致，确证了其结构。
Synthesis of ethyl γ-bromobutyrate;
γ-溴代丁酸乙酯的合成
One-pot synthesis of 4-bromobutyl acetate;
一锅法合成4-溴丁基乙酸酯
Effect of Butylamine Roxatidine Acetas on gastric juice excretion in rats with gastric ulcer
正丁胺基罗沙替丁乙酸酯对胃溃疡大鼠胃液分泌的影响
Synthesis and Inhibition of Gastric Juice Acid of Roxatidine Acetate and Its Analogues;
罗沙替丁乙酸酯及其类似物的合成与抑酸活性研究
Synthesis and characterization of the derivatives of roxatidine and study of activity
罗沙替丁乙酸酯衍生物的合成和抗溃疡活性的研究
The Mechanism of Affecting Ulcer Healing of Butylamine Roxatidine Acetate in Gastric Ulcer Rats Indued by Acetic Acid
正丁胺基罗沙替丁乙酸酯影响乙酸诱发胃溃疡大鼠溃疡愈合作用机制研究
Effect of Butylamine Roxatidine Acetas on Experimental Gastric Ulcer and Its Acute Toxicity
正丁胺罗沙替丁乙酸酯对动物实验性胃溃疡及急性毒性实验的影响
Investigation on the pharmacokinetics of iv gtt single and multi-dose roxatidine acetate hydrochloride injection in healthy volunteers
注射用盐酸罗沙替丁醋酸酯健康人体的药动学
Selecting Developing Agent in Synthesis Process of Roxatidine Acetate by TLC
罗沙替丁醋酸酯合成的薄层色谱展开剂的选择
Influence of butylamine roxatidine acetate on seroactive fractions in rats with gastric ulcer
正丁胺基罗沙替丁乙酸脂对胃溃疡大鼠胃黏膜活性因子的影响
ethyl ionylidene acetate
乙酸乙基紫罗兰叉酯
polyethylene glycol fumarate
聚反丁烯二酸乙二醇酯
dimercaptoethyl maleate
顺丁烯二酸二巯基乙酯
dibutoxy ethyl sebacate
癸二酸二丁氧基乙酯
diethyl butylmalonate
正丁基丙二酸二乙酯
n-Butyl acetate for industrial use
GB/T3729-1991工业乙酸丁酯
ethylene-butyl acrylate copolymer
乙烯-丙烯酸丁酯共聚物
ethyl-t-butyl peroxyoxalate
过氧草酸乙基特丁酯
butyl acetoxystearate
乙酰氧基硬脂酸丁酯
acetyltributyl citrate
柠檬酸乙酰三丁基酯