(2S,3S,5S)-2,5-Diamino-3-hydroxy-1,6-diphenylhexane, the key intermediate of lopinavir was synthesized from L-phenylalanine by N,O-benzylation, cyanidation, Grignard reaction and reduction to give (2S,3S,5S)-5-amino-2-dibenzylamino-1,6-diphenylhexan-3-ol, which was subjected to debenzylation with an overall yield of about 63%.
L-苯丙氨酸用氯苄进行N,O-苄基化、氰化、格氏反应、还原制得(2S,3S,5S)-5-氨基-2-二苄胺基-1,6-二苯基-3-己醇,再经钯炭催化脱苄制得抗病毒药洛匹那韦中间体(2S,3S,5S)-2,5-二氨基-3-羟基-1,6-二苯基己烷,总收率约为63%。
Study on the Synthesis of the Core Unit of Ritonavir and Lopinavir;
抗艾滋病药物利托那韦和洛匹那韦核心结构的合成研究
he is a small beast from Lower Boulonnais.
那是一匹下布洛涅种的小牲口。
The rest of the field is / are far behind Shalock.
其余的马都远远落在名叫夏洛克的那匹马后面。
Simultaneous and Rapid Determination of Aciclovir, Ganciclovir and Penciclovir in Plasma Using Solid-phase Extraction and High-performance Liquid Chromatography;
SPE-HPLC法同时快速测定血浆中更昔洛韦、阿昔洛韦和喷昔洛韦的浓度
Dumfries & Galloway
阿邓弗里斯-盖洛韦
Ms. Galloway works in the nation's capital.
加洛韦女士在首都工作，
Mallory - Weiss syndrome
马洛莱-韦斯征候群
Comparison of Effects of Ganciclovir and Acyclovir on Adult Varicella
更昔洛韦和阿昔洛韦治疗成人水痘的疗效比较
Method for determining ganciclovir quantity contained in ganciclovir cream
更昔洛韦乳膏中更昔洛韦含量测定方法的研究
Therapeutic effects of ganciclovir and aciclovir on varicella
更昔洛韦与阿昔洛韦治疗水痘临床疗效分析
But not to worry: it all . . . falls into place in the book's second half, where the language is plainer(Hallowell Bowser)
但别担心：它全都在书的后半部分，那儿的语言浅显一些(哈洛韦尔 鲍瑟)
A HPLC method was established for the determination of Aciclovir in Aciclovir urea cream.
建立阿昔洛韦尿素乳膏中阿昔洛韦含量的HPLC测定方法。
In 153 cases of prevention research,88 were in GCV group and 65 in ACV group;
预防研究共153例，更昔洛韦组88例，阿昔洛韦组65例。
Objective:To investigate the clinic response of genital herpes (GH) treated by acyclovir (ACV) and valacyclovir(VCV).
目的:观察阿昔洛韦与万乃洛韦治疗生殖器疱疹的临床疗效。
Objective:To investigate the clinic response of herpes zoster (HZ) treated by acyclovir (ACV) and valacyclovir (VCV).
目的:观察阿昔洛韦与万乃洛韦治疗带状疱疹的临床疗效。
Research of Antiviral Activity of Ganciclovir and Acyclovir to Varicella-zoster Virus in Vitro;
更昔洛韦与阿昔洛韦体外抗水痘—带状疱疹病毒活性的研究
Content determination of ganciclovir in Ganciclovir Sodium Chloride Injection by UV
紫外分光光度法测定更昔洛韦氯化钠注射液中更昔洛韦的含量
Determination the Content of Ganciclovir in Ganciclovir Gel by HPLC
高效液相色谱法测定更昔洛韦凝胶剂中更昔洛韦的含量