Methods:We observed the effects on c-Fos protein expression in lateral habenular nucleus and medial habenular nucleus after injecting cocaine into a belly cavity and spontaneous and evoked discharge of pain-correlative unit through iontophoresis of cocaine into LHb.
方法:腹腔注射可卡因,观察内、外侧缰核神经元c-Fos蛋白的表达;在外侧缰核微电泳可卡因,观察其痛相关神经元自发及痛诱发放电的改变;应用全细胞膜片钳技术观察可卡因对外侧缰核神经元延迟整流K+电流的影响。
To investigate the eletrophysiological effect of rat adrenomedullin (rADM) on barosensitive neurons in the rostral ventrolat- eral medulla (rVLM) and its potential mechanisms,the extracellular recording and multi-barrel iontophoresis methods were used.
采用多管微电泳结合细胞外记录的方法研究了肾上腺髓质素(adrenomedullin,ADM)对大鼠延髓头端腹外侧区(rostral ven- trolateral medulla,rVLM)压力反射敏感性神经元电活动的作用及其可能机制。
Objective To observe the direct effects of microelectrophoresis applications of substance P (SP) and SP antagonist on the spontaneous firing actives of arcuate nucleus (ARC) neuron in female dioestrum rat,and probe into the effect and mechanism of substance P on the control action of reproduction.
目的 观察微电泳P物质(SP)及其拮抗剂对间情期雌性大鼠弓状核(ARC)神经元自发放电活动的影响,进一步探讨整体情况下SP对生殖活动的调节作用及作用机制。
Methods: The effects of microelectrophoresis of CORT on the discharge of the presympathetic neurons in the RVLM were observed by extracellular recording in urethane-anaesthetized rats.
方法 :本研究采用细胞外记录和微电泳等方法观察CORT对氨基甲酸乙酯麻醉大鼠RVLM前交感神经元的作用 ,观察分别给予ACh受体拮抗剂阿托品 (ATR)、筒箭毒 (d TC)或六烃季铵 (C6)后CORT对RVLM前交感神经元的影响。
Aim: To research the spontaneous firing activities during different-frequency stimulation of subthalamic nucleus and microelectrophoresis GABA,Glu and their antagons respectively,approaching the mechanism of DBS in the treatment of Parkinson\'s disease further.
目的:观察电刺激丘脑底核(STN)及微电泳γ-氨基丁酸(GABA)、谷氨酸(Glu)及其对应的拮抗剂等对大鼠黑质网状部(SNr)神经元放电的影响,进一步探讨电刺激治疗帕金森病(PD)的机制。
The effects of microiontophoresis of corticostersone sulfate (CORT) on the discharge of the cardiovascular neurons in the RVLM were observed.
方法细胞外记录氨基甲酸乙酯麻醉的ＳＤ大鼠头端延髓腹外侧区（ＲＶＬＭ）被鉴定的心血管神经元的自发放电，观察微电泳硫酸皮质酮（Ｏ３ＲＴ对心血管神经元活动的影响，及其 ＧＣ受体拮抗剂 ＲＵ ４８６对ＣＯＲＴ导致神经元作用的影响。