METHODS After 7-day administration,the immobility time in the tail suspension test and forced swimming test in mice was observed.
方法:用药物给小鼠灌胃7d后,观察小鼠在悬尾试验,强迫游泳试验中不动时间的变化情况以及小鼠开野试验中自主活动变化情况。
Three active compounds,J01113,J01114 and J10745 were selected to test their antidepressant effects by mouse forced swimming and the tail suspension tests.
方法 采用高通量筛选方法在 5 0 0 0多种化合物中筛选具有 5 HT重摄取抑制作用的活性化合物 ,然后应用行为绝望抑郁模型———小鼠游泳试验和小鼠悬尾试验探讨活性化合物J0 1113 ,J0 1114和J10 745的抗抑郁作用。
Methods:The present study utilized mice forced swimming test, tail suspension test and reserpine reversal test.
方法:小鼠悬尾、小鼠强迫游泳及利血平拮抗实验。
METHODS The antidepressant effect of Yukexin capsules in mice were evaluated using several modules of depression,including the tail suspension test(TST),forced swimming test(FST)and reserpine-induced ptosis.
方法:选择小鼠强迫游泳、悬尾应激及利血平所致眼睑下垂小鼠抑郁模型,用郁可欣胶囊对其进行治疗观察。