Genetic polymorphisms of drug-metabolizing enzymes CYP2C19,NAT2,and TPMT in a Han Chinese population from He-nan area;
河南地区汉族人群药物代谢酶CYP2C19，NAT2和TPMT基因多态性分析(英文)
AIM: To evaluate the alterations of maternal hepatic drug-metabolizing enzymes and antioxidative function in tobacco-induced intrauterine growth retardation (IUGR).
目的:研究和探讨吸烟所致宫内发育迟缓(IUGR)大鼠母体肝脏药物代谢酶活性和抗氧化功能的改变及其所带来的毒理学和药理学意义。
Drug-metabolizing enzymes in many Western drug or Chinese medicine metabolism play a very important role.
药物代谢酶在众多中西药物代谢中起着非常重要的作用。
Progress in the effects of garlic on the activity of drug metabolic enzymes and transporters;
大蒜对药物代谢酶及转运体活性影响研究进展
Objective: To promote the study of drug metabolic enzymes in clinical practice.
目的:为了促进药物代谢酶在临床上的深入研究。
Both drug metabolic enzyme and transport protein are the key factors that govern the transport and metabolism of drugs in the human body.
药物代谢酶和转运蛋白是决定药物体内过程的关键因素,底物对它们的抑制或诱导作用是药物联合应用时产生药动学相互作用的主要机制。
Drug metabolism enzymes(DME) play a significant role in drug detoxification and activation,which exert important effect on drug efficacy and sensitivity to toxicity.
药物代谢酶(DME)在药物代谢解毒和药物代谢活化中起着重要的作用,对组织器官的药物效应和毒性的易感性产生重要影响。
Objective:The effects of the 20 Chinese Patent Medicines on the catalytic activities of five main drug metabolism enzymes of human liver microsome,CYP1A2,CYP2C9,CYP2C19,CYP2D6 and CYP 3A4,were assessed.
目的:考察六神丸等20个常用中成药对CYP1A2、CYP2C9、CYP2C19、CYP2D6和CYP3A4这5个人肝微粒体中主要的药物代谢酶的活性是否有影响。
The levels of liver microsomal protein,cytochrome P-450(Cyt P-450)and b 5(Cyt b 5 ),liver drug-metabolizing enzymes were determined,respect.
于感染后第 3,6 ,9,11和 13周分别宰杀 12只 (感染组 8只 ,对照组 4只 )大鼠 ,测定其肝微粒体蛋白、细胞色素P 4 5 0、细胞色素b5的浓度和肝脏药物代谢酶活性。
【Result】 Intraperitoneal injection of Streptococcus suis resulted in a time-dependent modulation of hepatic drug-metabolizing enzymes activities in mice.
【目的】评价猪链球菌感染对小鼠肝脏药物代谢酶活性的影响。
Effects of quinolones on activity of hepatic drug-metabolizing enzymes in Paralichthys olivaceus
喹诺酮类药物对牙鲆肝药物代谢酶活性的影响
Drug-Metabolizing Enzymes and Transporters: Roles in the Human Prostate Cancer Chemotherapy
药物代谢酶及转运体与前列腺癌药物治疗
Effects of Components in the Commonly Used Traditional Chinese Medicines on the Activity of Cytochrome P450 3A4
常用中药成分对药物代谢酶CYP3A4活性的影响
Effect of Hepatic Drug Metabolizing Enzymes in Mice Treated with Extract of Scutellariae Barbatae;
半枝莲粗提物对小鼠肝脏药物代谢酶的影响
Establish a Microbial Model with the Activity of Drug-metabolizing Enzyme CYP2C9;
建立具有药物代谢酶CYP2C9活性的微生物模型
Study on Key Techniques and Application of Genechip for Drug Metabolizing Enzyme Genotyping;
药物代谢酶基因分型芯片关键技术及应用研究
The Study on the Effect of Proton Pump Inhibitors on the Activities of Cytochrome P4501A2, N-Acetyltransferase2 and Xanthine Oxidase in Human;
质子泵抑制剂对药物代谢酶CYP1A2、NAT2和XO的影响
Research on Function and Oligonucleotide Microarray Detection of Cytochrome P450 Hot Mutation;
药物代谢酶CYP450热点突变检测芯片的研制与应用
The Study on the Effect of Ginkgo Biloba Tablets on the Activities of Cytochrome P4501A2, Cytochrome P4502A6, N-Acetyltransferase2 and Xanthine Oxidase in Human;
银杏叶片对人药物代谢酶CYP1A2、CYP2A6、NAT2和XO的影响
Research on the Mechanism of Incompatibility between Veratrum Nigrum and Ginseng Based on Cytochrome P450;
基于药物代谢酶的藜芦与人参配伍禁忌研究
Effect of Ginkgo Biloba Tablets on Activity of Cytochrome P_(450)1A2 and N-acetyltransferase 2 in Human
银杏叶片对人药物代谢酶CYP1A2与NAT_2活性的影响
Effect of ginkgo biloba tablets on Cytochrome P4502A6,XO and N-acetyltransferase 2 activity in human
银杏叶片对人药物代谢酶CYP2A6、XO和NAT2活性的影响
Evaluation of influence of Andrographis paniculata on activities of CYP1A2,CYP3A4,CYP2E1 and CYP2C19 genotypes in chickens by multiple cytochrome P450 probe substrates
用多种探针药物评价穿心莲对鸡药物代谢酶活性的影响
Influence of Borneolum Syntheticum on Cytochrome Enzymes in Liver Microsome;
冰片单次和多次给药对肝脏微粒体药物代谢酶的影响
Impairment of liver drug metabolizing enzymes in experimental Fascioloses in water buffalo
实验感染肝片吸虫对水牛肝脏药物代谢酶的损伤作用
The Study on the Effect of Compound Danshen Dripping Pills on the Activities of Cytochrome P4501A2, Cytochrome P4502A6, N-Acetyltransferase2 and Xanthine Oxidase in Human;
复方丹参滴丸对人药物代谢酶CYP1A2、CYP2A6、NAT2和XO的影响
Association Study of Polymorphisms in the Human Drug Metabolism Enzyme Gene and Bladder Cancer Risk;
药物代谢酶基因多态性与膀胱癌易感性关系研究
Cytochrome P450 and Anticancer Drug Metabolism;
细胞色素P450酶和抗癌药物代谢研究