Reorientation of T cell receptors during immunological synapse formation:a vortex-driven model;
免疫突触形成过程中T细胞受体的重定向运动:涡旋驱动模型
The specific cytotoxic effect of tumor infiltrating lymphocytes transfected with chimeric T cell receptor on cells which express KDR;
表达嵌合性T细胞受体的肿瘤浸润淋巴细胞对KDR表达阳性细胞的选择性杀伤作用
Analysis of T cell receptor VγI-Jγgene rearrangement in elderly patients with acute leukemia;
老年人急性白血病T细胞受体VγI-Jγ基因重排分析
Objective To construct a retroviral vector of the chimeric TCR, which comprises scFv-anti-erbB2, CD8 hinge region and CD3ζ by gene engineering technology.
目的利用基因工程技术构建表达嵌合T细胞受体(ch-TCR)分子的逆转录病毒载体(由抗 erbB2的单链抗体和信号传导链CD3ζ组成),感染预先刺激的小鼠T细胞,使得T细胞能以MHC非限制性的方式在体外识别并杀伤肿瘤细胞,为肿瘤的过继性免疫治疗提供新思路。
Objective: To clone human T cell receptor (TCR) ζ chain gene and express its encoding protein by baculoviral expression system in insect cells.
目的 :克隆人T细胞受体 (TCR) ζ链基因 ,运用昆虫杆状病毒系统表达该蛋白。
Method Clinicopathologic study, immunohistochemical staining by LSAB method, TCR β and TCR γ gene rearrangement analysis and detection of EBV DNA by PCR technique, EBER in situ hybridization(ISH) and detection of cell apoptosis by in situ end labeling of fragmented DNA technique were.
方法 :过去 15年中对近 2 0 0例“中线恶网”病例做了一系列研究 ,包括临床病理分析、LSAB法免疫组化染色作免疫表型分析、用PCR技术作T细胞受体β和γ链基因重排及EBV DNA检测、EBER原位杂交和原位末端标记DNA片段技术检测细胞凋亡。
Objective To investigate the expression and clonality of T cell receptor (TCR) Vβ repertoire in cord blood T cells induced by PML-RARα peptide in vitro.
目的了解PMLRARα多肽诱导脐血T细胞的T细胞受体(TCR)Vβ谱系表达和克隆性情况。
ObjectiveTo explore the immune pathogenesis of aplastic anemia (AA) and the therapeutic effects of Shengxue Mixture (SM) through the gene expressions of subfamilies of T-cell receptor variable region β (TCR Vβ) using immunologic and molecular biologic technology.
目的利用免疫学和分子生物学技术,着重从T细胞受体β链可变区(TCR Vβ)亚家族基因表达角度探讨再生障碍性贫血(AA)的免疫发病机制及中药复方生血合剂的治疗作用。
A Preliminary Study on Induction of Immune Tolerance by Oral Administration of Platelet Antigen in an Experimental Model of Immune Thrombocytopenia;
口服抗原诱导免疫性血小板减少模型T细胞耐受的实验研究
Roles of Different Subsets of T Lymphocytes in Portal Venous Injection Induced Tolerance
门静脉输注诱导耐受中CD4~+T细胞和CD8~+T细胞的不同作用
Progress on the regulatory T cells and immune tolerance in organ transplantation
调节性T细胞与器官移植免疫耐受的研究进展
Investigation of T Cellular Immunologic Tolerance Induced by mIDO Gene-transfected Tissue Engineering Chondrocytes;
IDO基因转染组织工程化软骨细胞诱导T细胞免疫耐受的研究
Effect of Jagged-1 on the Immunotolerance Induced by Dendritic Cell-mediated T Cells;
Jagged-1在树突状细胞介导T细胞诱导免疫耐受中的作用
Induction of immune tolerance and the importance of CD4~+CD25~+ regulatory T cells in mice liver transplantation
肝移植受体免疫耐受的诱导及CD4~+CD25~+T细胞的重要作用
T Cell Vaccine Induced Immune Tolerance of Simultaneous Pancreas and Kidney Transplantation in Rat;
T细胞疫苗诱导大鼠胰肾联合移植免疫耐受的实验研究
Explore on the Role of CD4～+CD25～+ Regulatory T Cell in the Maternal-Fetal Tolerance;
CD4～+CD25～+调节性T细胞在母胎耐受中作用的探索性研究
Induction and Mechanism of Materno-fetal Immune Tolerance by Adoptive Transfer of the Paternal Antigen-anergic CD4～+T Cells;
过继转输父系抗原anergic CD4～+T细胞诱导母—胎免疫耐受的分子机制
Effective Mechanisms of the Transferred Embryo Antigen-Tolerant T Cells in the Pregnant Host;
过继转输的胚胎抗原耐受T细胞在宿主孕鼠体内的效应机制
The Study on the Induction of Immunotolerance to Naive T Cell Derived from CD34～+ Cell by MSCs in Vitro;
MSCs诱导体外分化来的Naive T细胞免疫耐受的实验研究
The Study of Correlation between T Cell Activiting and Immuno-tolerance on Chronic Hepatitis B;
慢性乙型肝炎T淋巴细胞活化与免疫耐受相关性的初步研究
Effect of CD4~+CD25~+ Regulatory T Cell on Recipient Immune Tolerance to Rat Cardiac Allografts;
CD4~+CD25~+调节性T细胞对大鼠同种异体心脏移植免疫耐受的作用研究
Research on the Mechanism of Indoleamine 2, 3-Dioxygenase in Tumor-induced Tolerance Through CD4~+CD25~+CD127~-/Foxp3~+ T Cells Generation;
吲哚胺2，3双加氧酶诱导调节性T细胞参与肿瘤免疫耐受机制研究
Experimental Study for Apoptosis of Activated T Cells to Induce Spontaneous Tolerance of Rat Liver Allografts;
T淋巴细胞凋亡诱导大鼠肝移植自发性免疫耐受的实验研究
Prevention of Hepatitis B Infection through Breaking Antigen-specific T Cell Tolerance;
通过打破抗原特异性T细胞免疫耐受控制慢性HBV感染
Molecular Mechanism of Ye's Lupus Formula on Induction of Peripheral Blood T Lymphocytes Tolerance in the Patients with Lupus Nephritis
叶氏狼疮方诱导狼疮肾炎患者T细胞免疫耐受分子机制研究
Study of the Relationship of Paired Immunoglubin-like Receptors and Its T Cells Link in Induction Dendritic Cells Tolerant in Mouse;
小鼠配对免疫球蛋白样受体及其介导的T细胞阶联与树突状细胞免疫耐受作用关系的研究