Objective:To study the effects of curcumin on the expression of the vascular endothelial growth factor(VEGF) and androgen-independent prostate cancer cell line PC-3,and to explore its anticarcinogenic mechanism.
目的:研究姜黄素对雄激素非依赖性前列腺癌细胞株PC-3细胞体外作用及其对血管内皮生长因子(VEGF)表达的影响,探讨其抗肿瘤的作用机制。
Objective To observe the effect of docetaxol on androgen-independent prostate cancer cell line PC-3 in vitro and in vivo.
观察PC-3细胞荷瘤裸鼠使用20mg/kg多西紫杉醇治疗前后的体重、肿瘤重量、血清PSA和肿瘤PSA免疫组化的变化。
Then synchronously treat PC-12 cells with TMPz at different concentrations, and directl y observe changes of nuclei with fluorescent dyes.
目的:通过制作谷氨酸诱导的PC-12细胞损伤模型,进一步探讨川芎嗪影响凋亡的作用机制。
Method:Nerve growth factor(NGF) was used to cultivate the PC-12 cells.
目的:研究复方海蛇胶囊对β-淀粉样蛋白(Aβ1~42)诱导的PC-12细胞凋亡的影响,探讨复方海蛇胶囊应用于痴呆的治疗机制。
Objective To explore the protective effects of erythropoietin(EPO)on apoptosis of PC-12 cells induced by β-amyloid peptide (Aβ25-35).
目的探讨促红细胞生成素(EPO)对β-淀粉样肽(Aβ)诱导的PC-12细胞凋亡的保护作用。
Knockdown of survivin expression using siRNA inhibits the growth of PC-3M cells;
Survivin-siRNA对前列腺癌PC-3M细胞增殖的抑制作用
METHODS: E2F decoy DNA,ARE decoy DNA and control decoy DNA were transfected into PC-3M cells with lipofectamine,respectively.
方法:采用脂质体lipofectam ine将E2F decoy DNA、ARE decoy DNA和control decoy DNA分别转染PC-3M细胞,MTT检测其对细胞增生的影响,倒置相差显微镜观察细胞形态变化,流式细胞术检测细胞凋亡率,并进行染色体DNA断裂的测定;通过RT-PCR检测转染的PC-3M细胞中c-Myc mRNA、cyc lin D1 mRNA表达水平的变化,通过W estern b lotting检测细胞中c-Myc蛋白、cyc lin D1蛋白表达水平的变化。
METHODS PC-3M cells were treated with DADAG,ODC activity was tested;cell proliferation was evaluated by sulforhodamine B ( SRB) assay;cell cycle distribution was detected by flow cytometry,the expression of Cdc2,Cyclin B1,p-Cdc2(Tyr15),Cdc25C, and Wee1 were detected by Western blot.
目的研究二乙酰二脱水卫矛醇(DADAG)对鸟氨酸脱羧酶(ODC)活性的影响及其对人前列腺癌PC-3M细胞增殖的作用,并初步探讨其可能的分子机制。
After 48h and 72h, cell morphology was seen to change; MTT assay was used to determine the inhibiting effects of PC-3 cell proliferation; RT-PCR method was used to study the regulative effect of Ren.
目的探讨人参胡核汤对人前列腺癌PC-3细胞的增殖抑制作用。
[ Objective] To study the changes of Metallothionein( MT) and Zinc transporter( ZnT) gene expression in the PC-3 cells exposed to cadmium.
[目的]研究镉对前列腺癌PC-3细胞中金属硫蛋白(Metalllothionein,MT)和锌转运体(Zinctransporter,ZnT)基因表达的影响。
[Results] Interruption of the survivin expression of prostate cancer cell pc-3 could induce the apoptosis of pc-3 cells.
[结果]阻断survivin在前列腺癌细胞pc-3中的表达后,能够引起 pc-3细胞的凋亡,其机制可能是由于活化了凋亡通路的caspase-3。
Influence of lead acetate on the expressions of Bax, Bcl-2 and p53 in PC-12 cells;
醋酸铅对PC-12细胞Bax、Bcl-2和p53蛋白表达的影响
Study on chemical constituents from Incarvillea arguta and their accelerating PC-12 cell differentiation;
毛子草化学成分及其促PC-12细胞的分化作用研究Ⅰ
Expressing Borna disease virus phosphoprotein in PC-12 cell and its influence on the cell proliferation
博尔纳病病毒磷蛋白在PC-12细胞内的稳定表达及对其增殖的影响
Establishment of PC-3 Cell Line Expressing BRP44 Stably and Efficiently;
稳定高效表达BRP44的PC-3细胞系的建立
The Inhibitory Effects of SiRNA Expression Vector on the Expression of Survivin Gene of Prostate Cancer PC-3 Cell;
RNAi对前列腺癌PC-3细胞survivin基因表达的抑制作用
Effect of Freezing and Medicine Coordination on the Viability of PC-3 Cells in Cryochemotherapy;
冷冻—药物联合损伤PC-3细胞活性的研究
The Effect of hmSD Knockdown on Proliferation and Migration of PC-3 Cell in Vitro;
hmSD沉默对PC-3细胞增殖迁移影响的体外研究
Proliferation and Apoptosis of PC-3 Cells Induced by Different Survivin-targeted siRNA
不同survivin siRNA对PC-3细胞增殖和凋亡的影响
Influence of Renshen Huhe Decoction on the Cell Cycle of Androgen-independent Prostate Cancer Line PC-3.
人参胡核汤对人前列腺癌PC-3细胞周期的影响
Effect of Interactions Between EGCG and Zn~(2+) on Energy Metabolism of PC-3 Cells
EGCG与锌离子互作对PC-3细胞能量代谢的影响
The Effect of Ellagic Acid on Prostate Cancer Cell Line PC-3
鞣花酸对前列腺癌PC-3细胞生长和凋亡的影响
Effects of TRPM8 on the proliferation and motility of prostate cancer PC-3 cells
TRPM8对前列腺癌细胞PC-3细胞增殖和迁移影响的研究
Effects of dihydroartemisinin on prostate cancer growth in vivo and expression of Caspase-3
双氢青蒿素对前列腺癌PC-3细胞体内生长及Caspase-3表达的影响
Study of the Expression Profile of KDR in the Prostatic Carcinoma and Its Role in PC-3 Cell Line;
KDR在人前列腺癌的表达及KDR反义寡核苷酸对PC-3细胞作用的研究
The Effect of the Lentivirus-mediated RNA Interference Targeting Survivin Gene on the Growth of PC-3 Cells in Vitro and Vivo;
慢病毒介导的survivin基因稳定干扰对PC-3细胞株体内外生长的影响
Chronic Administration of Valproic Acid Inhibits Prostate Cancer PC-3 Cell Growth;
丙戊酸长期给药抑制前列腺癌PC-3细胞生长的实验研究
Inhibition of CD147 Expression Reduces Tumor Cell Invasion in Human Prostate Cancer Cell Line via RNA Interference;
针对CD147 RNA干扰对前列腺癌PC-3细胞系侵袭作用的影响
The Effect of KLF6 Gene Recombinant Plasmid on Prostate Cancer Cell Line PC-3;
转染抑癌基因KLF6对前列腺癌PC-3细胞作用的实验研究
Study on Immune Adjustment of Mice Caused by PC-3 Cell Transferred mIL-18 and mGM-CSF Gene in Vivo and in Vitro;
IL-18和GM-CSF转染PC-3细胞后在小鼠体内外引起的免疫效应研究
Research of Vitamin E Succinate Induce Apoptosis in Prostate Cancer PC-3 Cells;
维生素E琥珀酸酯诱导前列腺癌PC-3细胞凋亡的实验研究
Study on Growth Interference of Dihydroartemisinin in PC-3 Cell Lines of Prostate Cancer in Vitro;
双氢青蒿素对前列腺癌PC-3细胞体外生长干扰的研究