analysis of the sequence from a Holstein calf afflicted with leukocyte adhesion deficiency (LAD), two point mutations were detected within the gene encoding bovine CD18: one mutation replaced adenine at the nucleotide 383 with guanine, and the other mutation replaced the cytosine at the nucleotide 775 with thymine.
从一患白细胞粘附缺陷症（ＬＡＤ）的黑白花奶牛犊的核苷酸顺序分析中，发现牛的抗原分子分化群１８（ＣＤ１８）的基因密码有二处发生了点突变；一处在第３８３核苷酸上，在此处原有的腺瞟吟已被鸟嘌呤取代；另一处在第７７５核苷酸上，在此处原有的胞嘧啶被胸腺嘧啶取代了。