The methods of asymmetric construction of quaternary carbon centers and its applications to the synthesis of natural products have been reviewed.
综述了季碳的不对称构筑法及其在天然产物全合成中的应用。
The core innovation of this thesis involves the TiCl_4-mediated-tandem Semipinacol rearrangement / intramolecular Schmidt reaction ofα-siloxy-epoxy-azide leading to a versatile and efficient approach to azaquaternary units.
本论文核心创新是四氯化钛促进下的α硅醚环氧叠氮化合物参与的Semipinacol重排／分子内的Schmidt串联反应，并以此建立了构建氮杂季碳结构单元的新方法。
The unequivocal chemical synthesis of δ-lactones, which were important intermediates in the synthesis of a variety of structures with biological and medical significance, such as antifungal and antitumor, has attracted wide attention in organic chemistry.
得到了具有一个季碳中心5，6—二氢—6，6二取代吡喃—2—酮化合物，它为很多天然产物和药物合成的中间体提供了一个简。
Asymmetric carbon-carbon bond cross-coupling reactions,especially the construction of all-carbon quaternary stereo center, are an important part of organic synthesis and still full of challenge.
不对称碳-碳键的合成反应,尤其是手性季碳中心的构建反应,是有机合成研究的一个重点和难点所在,对于有机合成的应用和发展具有重要意义。