Reversal of resistance of multidrug resistant MCF/Dox cell line to doxorubicin by a benflumetol derivative LY980503;
本芴醇衍生物LY980503逆转人乳腺癌多药耐药细胞株MCF/DOX对多柔比星的耐药性
AIM: A new route of synthesis of benflumetol(I) by 5 step reactions was developed.
目的：设计了抗疟药本芴醇（Ｉ）的５ 步合成新路线。
A series of β-amino alcohols have been synthesized by the reaction of fluorine oxirane with aromatic amines in the presence of alumina.
在ZrOCl2·7H2O催化下用胺与芴环氧乙烷反应,合成一系列β-氨基芴醇类化合物,所有目标产物的结构均由1HNMR,IR,MS确定。